首页> 外国专利> Soluble recombinant antigen protein of porcine epidemic diarrhea virus and vaccine composition for preventing or treating porcine epidemic diarrhea comprising the same

Soluble recombinant antigen protein of porcine epidemic diarrhea virus and vaccine composition for preventing or treating porcine epidemic diarrhea comprising the same

机译:猪流行性腹泻病毒的可溶性重组抗原蛋白和用于预防或治疗猪流行性腹泻的疫苗组合物

摘要

The present invention relates to a water-soluble recombinant antigen protein derived from porcine epidemic diarrhea virus and a vaccine composition for preventing or treating swine epidemic diarrhea comprising the same, which is safer and more economical to prevent porcine epidemic diarrhea (PED) Subunit vaccine has been developed as a strategy to respond more quickly when it occurs. In the case of the live attenuated vaccine of the present invention, it is difficult to respond to the emergence of the new variant virus rapidly due to the inconvenience of long-term subculture (100 times) in animal cells. However, Because it is possible to produce by simple substitution of gene sequence, it can cope quickly. Accordingly, it is expected that the present invention can be used as an oral vaccine together with a vaccine or vaccine carrier for prevention or treatment of swine epidemic diarrhea as an animal medicine.
机译:本发明涉及源自猪流行性腹泻病毒的水溶性重组抗原蛋白和用于预防或治疗猪流行性腹泻的疫苗组合物,其预防和预防猪流行性腹泻(PED)亚单位疫苗更安全,更经济。被开发为一种可以在发生时更快做出响应的策略。在本发明的减毒活疫苗的情况下,由于动物细胞中长期传代培养(100次)的不便,难以快速响应新变体病毒的出现。但是,由于可以通过简单地替换基因序列来产生,因此可以迅速应对。因此,期望本发明可以与动物用药物一起用于预防或治疗猪流行性腹泻的疫苗或疫苗载体与口服疫苗一起使用。

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