The varied porcine epidemic diarrhea virus and vaccine composition for preventing epidemic diarrhea using the same

摘要

The present invention relates to a mutant porcine epidemic diarrhea virus and a vaccine composition for the prevention of epidemic diarrhea using the same, and more particularly, to a mutant porcine (e. G., Porcine) virus, deposited with KCTC, epidemic diarrhea virus) QIAP1401-70P and a virus inactivated thereof as an active ingredient. Since the novel virus belongs to the same G2b gene as the recently introduced mutated pandemic diarrhea virus, it is very similar to genetically. Therefore, when the virus is inactivated and used as a vaccine, it can not only prevent the recent pandemic influenza diarrhea more effectively, And immunogenicity. In addition, it has excellent proliferation ability in Vero cells, which is advantageous in mass production through in vitro proliferation. The novel viruses of the present invention exhibit a wide range of pathogenicity ranging from piglets aged 3 days to pigs growing up to 11 weeks, and thus can be usefully used as viruses for attack inoculation for vaccine development or testing. It is expected.