Method for detecting LINE-1 global DNA methylation in Rat

摘要

TECHNICAL FIELD The present invention relates to a method for detecting whether a rat-specific global DNA methylation has occurred, and more particularly, to a method for detecting whether or not a rat-specific global DNA methylation has occurred, will be. By performing amplification of the LINE-1 CpG site specifically in the global DNA methylation analysis of rats through the method according to the present invention, it is possible to carry out an animal evaluation test of environmental pollutants at a polymer level using LINE-1 as a biomarker, Similarly, it can be used for diagnosis or treatment monitoring of various diseases that can make LINE-1 methylation a diagnostic marker, and for diagnosis of prognosis.