首页> 外国专利> Antimicrobial peptide with improved specificity to gram-negative pathogen and antimicrobial composition comprising the same

Antimicrobial peptide with improved specificity to gram-negative pathogen and antimicrobial composition comprising the same

机译:对革兰氏阴性病原体具有改善的特异性的抗微生物肽和包含该肽的抗微生物组合物

摘要

The present invention relates to a novel antimicrobial peptide and an antimicrobial composition containing the antimicrobial peptide, and more particularly, to an antimicrobial peptide having an antimicrobial activity and an antiinflammatory activity with enhanced specificity against gram-negative bacteria and an antimicrobial composition containing the antimicrobial peptide . The antimicrobial peptide according to the present invention exhibits high specificity and low cytotoxicity against Gram-negative bacteria and has excellent anti-inflammatory and antimicrobial activity effects by inactivating LPS by binding to LPS acting as endotoxin, It can be usefully used as a composition for antibiosis specific for a pathogen.;
机译:本发明涉及新型抗菌肽和含有该抗菌肽的抗菌组合物,更具体地,涉及对革兰氏阴性菌具有增强的特异性的具有抗菌活性和抗炎活性的抗菌肽以及包含该抗菌肽的抗菌组合物。本发明的抗菌肽对革兰氏阴性菌表现出高特异性和低细胞毒性,并且通过与作为内毒素的LPS结合而使LPS失活而具有优异的抗炎和抗菌活性效果,可以有效地用作抗菌剂特定于病原体。

著录项

  • 公开/公告号KR101838208B1

    专利类型

  • 公开/公告日2018-03-13

    原文格式PDF

  • 申请/专利权人 경상대학교 산학협력단;

    申请/专利号KR20160015464

  • 发明设计人 조주현;김현;장주혜;

    申请日2016-02-11

  • 分类号C07K7/06;A01N63/02;A23K1/16;A23L3/3463;A61K8/64;A61Q19/00;C07K7/08;

  • 国家 KR

  • 入库时间 2022-08-21 12:38:14

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