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Pharmaceutical composition for inducing exercise-mimetic effects

机译:诱导模拟运动效果的药物组合物

摘要

The present invention relates to a pharmaceutical composition for inducing exercise-like effects comprising an 1-adrenergic receptor agonist or a pharmaceutically acceptable salt thereof as an active ingredient, and a use thereof. The 1-adrenergic receptor agonist of the present invention increases the expression of p-AMPK, PPAR, and PGC-1 , which play a key role in maintenance and regulation of energy metabolism activity in vivo, In addition to increasing glucose uptake, inhibiting adipocyte differentiation and lipid accumulation, decreasing abdominal fat and body weight, controlling metabolic disorders of mitochondria and inhibiting inflammation, Metabolic diseases, cardiovascular diseases, inflammatory diseases, etc.).;
机译:本发明涉及用于诱导运动样效果的药物组合物,其包含1-肾上腺素能受体激动剂或其药学上可接受的盐作为活性成分,及其用途。本发明的1-肾上腺素能受体激动剂增加p-AMPK,PPAR和PGC-1的表达,它们在维持和调节体内能量代谢活性中起关键作用,除了增加葡萄糖摄取,抑制脂肪细胞外分化和脂质积累,减少腹部脂肪和体重,控制线粒体的代谢紊乱并抑制炎症,代谢性疾病,心血管疾病,炎症性疾病等);

著录项

  • 公开/公告号KR101845952B1

    专利类型

  • 公开/公告日2018-04-06

    原文格式PDF

  • 申请/专利权人 주식회사 셀버틱스;

    申请/专利号KR20160122779

  • 发明设计人 서홍석;이용직;김응주;김현수;

    申请日2016-09-26

  • 分类号A61K31/16;A61K31/122;A61K31/165;

  • 国家 KR

  • 入库时间 2022-08-21 12:38:02

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