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SIRT1 Methods for Regulating Differentiation of kidney precursor Cells from Embryonic Stem Cells Through modulation of SIRT1 expression

机译:SIRT1通过调节SIRT1表达来调节肾脏前体细胞与胚胎干细胞分化的方法

摘要

The present invention relates to a method for regulating the differentiation of progenitor precursor cells from embryonic stem cells by controlling the expression of SIRT1 (silent mating type information regulation 2 homolog: sirtuin 1) The kidney cells or the kidney precursor cells produced by the differentiation induction method can be utilized for tissue regeneration and can be used as a composition for regulating differentiation of progenitor precursor cells by administration of SIRT1 inhibitor or promoter.
机译:本发明涉及通过控制SIRT1的表达来调节祖先前体细胞从胚胎干细胞的分化的方法(沉默交配型信息调节2同源物:sirtuin 1)分化诱导产生的肾细胞或肾脏前体细胞该方法可以用于组织再生,并且可以用作通过施用SIRT1抑制剂或启动子来调节祖细胞前体细胞分化的组合物。

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