TREATMENT OF 'IQ MOTIF CONTAINING GTPASE ACTIVATING PROTEIN' IQGAP RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO IQGAP

摘要

The present invention relates to an antisense oligonucleotide that modulates the expression and / or function of an IQ motif containing a GTPase activating protein (IQGAP), in particular to a natural antisense polynucleotide of an IQ motif containing an GTPase activating protein (IQGAP) Lt; RTI ID = 0.0 oligonucleotides / RTI The invention also relates to the identification of such antisense oligonucleotides and to the use thereof for the treatment of diseases and disorders associated with the expression of IQGAP.