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- Composition comprising a phenylalanine-chloroquine derivative as an active ingredient for preventing and treating malaria infection
- Composition comprising a phenylalanine-chloroquine derivative as an active ingredient for preventing and treating malaria infection
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机译:-包含苯丙氨酸-氯喹衍生物作为预防和治疗疟疾感染的活性成分的组合物
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摘要
The present invention relates to a composition for treating and preventing a malaria infectious disease comprising a phenylalanine-chloroquine derivative compound represented by the aforementioned general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient, In vitro anti-malarial efficacy search using Plasmodium falciparum as an anti-malarial activity against phenylalanine-chloroquine derivatives (Experimental Example 1); (Experimental Example 2), it was confirmed that the anti-malarial activity of the novel compounds was excellent. As a result, a novel diatomic phenylalanine-chloroquine derivative compound or a pharmaceutically acceptable salt thereof was obtained as an active ingredient As an anti-malarial agent.
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