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APPLICATION OF LAMININ IN CULTURE OF CORNERAL ENDOTHELIAL CELLS

机译:层粘连蛋白在角膜上皮细胞培养中的应用

摘要

The present invention provides a method of culturing corneal endothelial cells. More specifically, the present invention provides a composition for culturing or growing corneal endothelial cells, comprising at least one agent consisting of laminins and fragments thereof which express in corneal endothelial cells. Specifically, the present invention can comprise laminin 511 (alpha5 beta1 gamma1) and laminin 512 (alpha5 beta2 gamma 1). The present invention further provides a culture container for corneal endothelial cells, which is coated with the composition of the present invention. Furthermore, the present invention provides a method for culturing corneal endothelial cells comprising the step of using the composition or the container of the present invention to culture the corneal endothelial cells.
机译:本发明提供了一种培养角膜内皮细胞的方法。更具体地,本发明提供了用于培养或生长角膜内皮细胞的组合物,其包含至少一种由层粘连蛋白及其在角膜内皮细胞中表达的片段组成的试剂。具体地,本发明可以包含层粘连蛋白511(α5β1γ1)和层粘连蛋白512(α5β2γ1)。本发明进一步提供了用本发明的组合物包被的用于角膜内皮细胞的培养容器。此外,本发明提供了一种用于培养角膜内皮细胞的方法,该方法包括以下步骤:使用本发明的组合物或容器来培养角膜内皮细胞。

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