METHOD OF PROCESSING DATA FROM HIGH-FLOW SEQUENCING TO PROCESS / ANALYZE NUCLEIC ACID SEQUENCES CORRESPONDING TO EXOME OR GENOME OF SEVERAL BIOLOGICAL SAMPLES

摘要

A method of processing data from high throughput sequencing to process / analyze the nucleic acid sequences corresponding to the exome or genome of several biological samples, to find, among said nucleic acid sequences, at least a gene possibly involved in a phenotype of interest, from the Vj variants in a given chromosome, taking the values from 1 to T, T being equal to the total number of variants detected in the chromosome, in which to perform queries on the variants Vj, bit vectors are calculated, the bits being used to note the membership of these variants Vj annotation categories so as to allow logical operations between the categories, the membership of these variants Vj being indexed by the genomic position of the variants Vj.