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System and method for identifying potential targets for pharmaceutical compound

机译:用于识别药物化合物潜在靶标的系统和方法

摘要

A system and method for identifying potential targets for a pharmaceutical compound. The system includes a database arrangement operable to store existing data sources and information related to the pharmaceutical compound; and a processing module communicably coupled to database arrangement. The processing module is operable to receive information related to the pharmaceutical compound, wherein the information includes at least one known target associated with the pharmaceutical compound; extract plurality of targets from existing data sources, wherein the existing data sources comprise plurality of data records and wherein each of the plurality of targets is associated with the pharmaceutical compound in at least one data record; analyse druggability of each of plurality of targets to determine a preliminary set of targets; determine net score for each of the targets in preliminary set of targets; and designate targets with a net score above a predefined threshold, as potential targets.
机译:用于识别药物化合物的潜在靶标的系统和方法。该系统包括数据库装置,该数据库装置可操作用于存储现有数据源和与该药物化合物有关的信息。通信连接到数据库装置的处理模块。所述处理模块可操作以接收与所述药物化合物有关的信息,其中所述信息包括与所述药物化合物有关的至少一个已知靶标;从现有数据源中提取多个靶标,其中现有数据源包括多个数据记录,并且其中多个靶标中的每个与至少一个数据记录中的药物化合物相关联;分析多个靶标中的每个靶标的可药用性,以确定一组初步的靶标;确定初步目标集中每个目标的净得分;并将净得分高于预定义阈值的目标指定为潜在目标。

著录项

  • 公开/公告号GB201804870D0

    专利类型

  • 公开/公告日2018-05-09

    原文格式PDF

  • 申请/专利权人 INNOPLEXUS AG;

    申请/专利号GB20180004870

  • 发明设计人

    申请日2018-03-27

  • 分类号

  • 国家 GB

  • 入库时间 2022-08-21 12:32:37

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