首页> 外国专利> BIOMIMETIC MEMBRANE FORMED FROM THREADS HAVING ATTACHED VESICLES

BIOMIMETIC MEMBRANE FORMED FROM THREADS HAVING ATTACHED VESICLES

机译:附着有囊泡的生物膜

摘要

Briefly, in one aspect of the invention, natural or genetically engineered proteins are incorporated into a polymeric vesicle that is conjugated to a thread to form a vesicle-thread conjugate. The engineered protein is preferably a transmembrane protein embedded in the wall of the polymeric vesicle. The vesicle-thread conjugate is then formed into a membrane or thin fabric having a wide variety of inherent functionality, including the ability to selectively transport and/or filter compounds between fluids. By selecting proteins with specific properties, membranes can be fabricated with a defined functionality including molecular scale addressability via directed electrostatic, electromagnetic, and chemical forces.
机译:简而言之,在本发明的一方面,将天然或基因工程化的蛋白质掺入聚合物囊泡中,所述聚合物囊泡缀合至线以形成囊泡-线缀合物。所述工程蛋白优选是包埋在聚合物囊泡壁中的跨膜蛋白。然后将囊泡-线缀合物形成具有多种固有功能的膜或薄织物,所述固有功能包括选择性地在流体之间运输和/或过滤化合物的能力。通过选择具有特定特性的蛋白质,可以通过限定的功能(包括通过定向的静电,电磁和化学力实现分子规模可寻址性)制造膜。

著录项

  • 公开/公告号EP2344269B1

    专利类型

  • 公开/公告日2019-08-28

    原文格式PDF

  • 申请/专利权人 APPLIED BIOMIMETIC A/S;

    申请/专利号EP20090743846

  • 发明设计人 MONTEMAGNO CARLO D.;

    申请日2009-10-06

  • 分类号B01D69/02;B01D69/12;H01G9/20;B01D61/02;

  • 国家 EP

  • 入库时间 2022-08-21 12:31:37

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