首页> 外国专利> ADJUVANT FOR TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME

ADJUVANT FOR TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME

机译:含该药物的经皮或经皮给药的辅助剂和药物制剂

摘要

It is intended to provide a low molecular weight adjuvant which can be administered safely without inducing skin irritation or the like by transdermal or transmucosal administration and is for enhancing immunogenicity of an antigen efficiently. It can be achieved by an immunostimulant adjuvant containing at least one substance selected from the group consisting of aliphatic alcohols, free fatty acids and fatty acid derivatives but does not contain a substance represented by the following formula. (In the formula, R 3 and R 4 may be combined to form a cyclic ring, and R 1 and R 2 independently represent an alkyl side chain having 1 to 16 carbon atoms.)
机译:本发明旨在提供一种低分子量佐剂,其可以通过经皮或透粘膜给药安全地给药而不会引起皮肤刺激等,并且可以有效地增强抗原的免疫原性。它可以通过包含至少一种选自脂族醇,游离脂肪酸和脂肪酸衍生物的物质但不包含下式代表的物质的免疫刺激佐剂来实现。(式中,R 3和R 4可以结合形成环,并且R 1和R 2独立地表示具有1至16个碳原子的烷基侧链。)

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