OPHTHALMIC COMPOSITIONS BASED ON POLYUNSATURATED FATTY ACIDS AND TRIACYLGLYCEROLS

摘要

The invention relates to topical ophthalmic preparations for the prevention and treatment of ocular pathologies, in particular inflammatory keratoconjunctivites and dry eye syndrome, which contain as the active ingredients omega-3 and/or omega-6 polyunsaturated fatty acids, such as EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid) and GLA (γ-linolenic acid), in solution in an oily vehicle dispersed in an aqueous gel containing one or more gelling polymers, wherein the oily vehicle is constituted by a vegetable or synthetic oil selected from the group consisting of: medium chain triglycerides (MCT), long chain triglycerides (LCT) liquid at room temperature, vegetable oils and their mixtures, and does not contain vitamin E or derivatives thereof having anti-oxidant activity. The preparations are particularly indicated for use as artificial tears, and are stable to long term storage even at room temperature.