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MULTIMODAL IMAGING SYSTEM AND METHOD FOR NON-INVASIVE EXAMINATION OF AN OBJECT

机译:非侵入性检查对象的多模态成像系统和方法

摘要

The invention relates to a multimodal imaging system (2) for the non-invasive examination of an examination object (10) comprising a multiphoton imaging system for providing high-resolution detail images of the examination subject (10) having a radiation source (12) which generates an excitation beam (21 ) near infrared femtosecond laser radiation for triggering a secondary radiation emitted by the examination object (10), and focusing optics (30), by means of which the radiation of the radiation source (12) can be directed to a measuring position of the examination object (10), the focusing optics (30) and a laser head (14) of the radiation source (12) are provided in a measuring head (4) which is freely pivotable, rotatable and flexibly positionable in space, so that the examination of the examination object (10) can be carried out under arbitrary solid angles, and with at least one Confocal detection device which at least partially with integrated into the measuring head (4) and adapted to receive a signal of the excitation beam (21) near infrared femtosecond laser radiation remitted by the examination subject (10). In addition, a method for non-invasive examination of an examination subject (10) using a multimodal Imaging system (2) and use of the multimodal imaging system (2) for examining living matter of the examination subject (10).
机译:本发明涉及一种用于对检查对象(10)进行非侵入式检查的多峰成像系统(2),该多峰成像系统包括用于提供具有辐射源(12)的检查对象(10)的高分辨率细节图像的多光子成像系统。其产生在红外飞秒激光辐射附近的激发光束(21),用于触发由检查对象(10)发出的二次辐射,以及聚焦光学器件(30),通过辐射光学器件可以引导辐射源(12)的辐射相对于检查对象(10)的测量位置,辐射源(12)的聚焦光学器件(30)和激光头(14)设置在测量头(4)中,该测量头可自由枢转,旋转和灵活定位因此,可以在任意立体角下使用至少一个共焦检测装置对检查对象(10)进行检查,该共焦检测装置至少部分集成在测量头(4)中,接收受检者(10)发射的近红外飞秒激光辐射的激发光束(21)的信号。另外,提供了一种用于使用多模式成像系统(2)对检查对象(10)进行非侵入式检查的方法,以及该多模式成像系统(2)用于检查检查对象(10)的生物的用途。

著录项

  • 公开/公告号EP3542710A1

    专利类型

  • 公开/公告日2019-09-25

    原文格式PDF

  • 申请/专利权人 JENLAB GMBH;

    申请/专利号EP20180163646

  • 发明设计人 KÖNIG KARSTEN;WEINIGEL MARTIN;

    申请日2018-03-23

  • 分类号A61B5;G01N21/64;G02B21;

  • 国家 EP

  • 入库时间 2022-08-21 12:28:30

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