ORAL PHARMACEUTICAL COMPOSITION COMPRISING A PHARMACEUTICALLY ACTIVE AGENT, AT LEAST ONE CATIONIC BIOADHESIVE POLYMER AND AT LEAST TWO ANIONIC POLYMERS

摘要

The present invention relates to a solid oral composition comprising a pharmaceutically active agent, such as, but not limited to an immunogenic agent (e.g., a vaccine), at least one cationic bioadhesive polymer which is preferably chitosan and at least two anionic compounds that allows the oral administration and delivery of the pharmaceutically active agent essentially unaltered to the intestinal mucosa; the present invention also relates to a process for preparing such solid oral composition and its use for vaccinating or boostering an animal consisting in administering orally for the intestinal delivery to said animal.