FUSION PROTEIN COMPRISING IMMOBILIZED PROTEIN WITH INCREASED ANTIOXIDATIVE FUNCTION AND SKIN CELL PROLIFERATION EFFECT AND HUMAN EPITHELIAL CELL GROWTH FACTOR, AND COSMETIC COMPOSITION CONTAINING FUSION PROTEIN AS ACTIVE INGREDIENT FOR IMPROVING SKIN WRINKLES

摘要

The present invention relates to a cosmetic composition for improving skin wrinkle with increased anti-oxidant activity and skin cell proliferation effect comprising, as an effective component, a fusion protein of antifreeze protein and human epidermal growth factor, and, as the fusion protein of the present invention has an excellent anti-oxidant activity and a high skin cell proliferation effect, it can be advantageously used as a raw material of a functional cosmetic having an excellent skin regeneration effect like improvement of skin wrinkles and skin whitening.