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SINGLE NUCLEOTIDE POLYMORPHISM INHLA-B*15:02
SINGLE NUCLEOTIDE POLYMORPHISM INHLA-B*15:02
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机译:单核苷酸多态性INHLA-B * 15:02
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摘要
Disclosed herein is a novel single nucleotide polymorphism (SNP) in HLA-B*15:02 that can be used as a biomarker for carbamazepine-induced severe adverse skin reactions in Asians. Also provided herein are methods and reagents for assessing the specific SNP, and applying the SNP in predicting an increased risk of carbamazepine-induced severe adverse skin reactions.
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