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ALIGNING A NON-SPHERICAL BIOLOGICAL ENTITY IN A SAMPLE FLOW USING AMBIENT VISCOELASTIC FLUID FLOWS
ALIGNING A NON-SPHERICAL BIOLOGICAL ENTITY IN A SAMPLE FLOW USING AMBIENT VISCOELASTIC FLUID FLOWS
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机译:使用环境粘弹性流体流动对样品流动中的非球面生物实体进行分类
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摘要
A technique is presented for aligning, in a desired region within a flow chamber of a flow cell, a non-spherical biological entity carried in a sample. The flow chamber has a rectangular cross-section. A bottom flow input module, a top flow input module and a sample input module provide a viscoelastic first fluid, a second viscoelastic fluid, and the sample, respectively, to the flow chamber. The first and the second viscoelastic fluids laminarly flow along a bottom and a top wall of the flow chamber and the sample laminarly flows sandwiched between them. By controlling rate of flow of the first and/or the second viscoelastic fluids the sample flow, and thus the non-spherical biological entity, is focused in the desired region. A gradient of sheer within the sample flow set up due to the first and second viscoelastic fluids orients the non-spherical biological entity in the desired region.
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