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HIGH-THROUGHPUT SCREENING FOR COMPOUNDS MODULATING EXPRESSION OF CELLULAR MACROMOLECULES
HIGH-THROUGHPUT SCREENING FOR COMPOUNDS MODULATING EXPRESSION OF CELLULAR MACROMOLECULES
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机译:调节细胞大分子表达的化合物的高通量筛选
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摘要
To provide a method of screening for compounds that modulate expression of specific macromolecules, or "targets."SOLUTION: A method of screening for compounds that modulate expression of specific macromolecules, or "targets," is particularly useful in that the method does not require separation of target-bound ligand and excess ligand and therefore enables, but is not limited to, high-throughput screening for compounds that increase or decrease expression levels or cellular levels of a target. The method can also be used for high-throughput diagnosis of a condition leading to an increase or decrease of a cellular macromolecule.SELECTED DRAWING: Figure 4
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