5- 2- (Pyridin-2-ylamino) -1,3-thiazol-5-yl -2,3-dihydro-1H-isoindol-1-one derivatives and two of phosphatidylinositol 3-kinase delta and gamma Its use as a heavy inhibitor

摘要

Certain novel compounds (including pharmaceutically acceptable salts thereof) that inhibit phosphatidylinositol 3-kinase gamma (PI3Kδ) and phosphatidylinositol 3-kinase gamma (PI3Kγ) activity, including asthma and chronic obstructive lung Compounds for the treatment and / or prevention of clinical conditions including respiratory diseases such as diseases (COPD), their use in therapy, pharmaceutical compositions containing them, and processes for preparing such compounds Is disclosed.