Combination therapy with BACE-1 inhibitor and anti-N3PGLU Abeta antibody

摘要

The present invention is a method of treating cognitive or neurodegenerative diseases, wherein an effective amount of a compound of formula or a pharmaceutically acceptable salt thereof is administered to a patient in need of such treatment with hE8L, B12L. , R17L, antibody I, and antibody II, in combination with an effective amount of an anti-N3pGlu Abeta antibody selected from the group consisting of antibodies II.