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Heterocyclic inhibitors of CBP / EP 300 and their use in the treatment of cancer

机译:CBP / EP 300杂环抑制剂及其在癌症治疗中的应用。

摘要

The present invention relates to compounds of formula (I) and formula (II) and salts thereof and compositions and uses thereof. The compounds are useful as inhibitors of CBP and / or EP300. Pharmaceutical compositions comprising a compound of Formula (I) or Formula (II), or a pharmaceutically acceptable salt thereof, and various CBP and / or EP300 mediated disorders (eg, cancer, inflammatory disorders, and autoimmunity Also included are methods of using such compounds and salts in the treatment of diseases.
机译:本发明涉及式(I)和式(II)的化合物及其盐及其组合物和用途。该化合物可用作CBP和/或EP300的抑制剂。包含式(I)或式(II)的化合物或其药学上可接受的盐以及各种CBP和/或EP300介导的疾病(例如,癌症,炎性疾病和自身免疫性)的药物组合物,还包括使用此类化合物的方法和盐治疗疾病。

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