TIE2 ACTIVATOR, AGENT FOR BLOOD VESSEL MATURATION, BLOOD VESSEL STABILIZER, AND ORAL COMPOSITION FOR TIE2 ACTIVATION

摘要

To provide a Tie2 activator, a neovascularization inhibitor, an agent for blood vessel maturation, an agent for blood vessel normalization, and a blood vessel stabilizer which have an excellent Tie2 activating action, neovascularization inhibitory action, blood vessel maturation action, blood vessel normalization action, and blood vessel stabilization action, and have high safety, and to provide a pharmaceutical composition.SOLUTION: The invention provides a Tie2 activator, a neovascularization inhibitor, an agent for blood vessel maturation, an agent for blood vessel normalization, and a blood vessel stabilizer which contain as an active ingredient at least one selected from Tilia miqueliana extract, and Aesculus hippocastanum extract, and a pharmaceutical composition containing at least any of them.SELECTED DRAWING: None