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HIGHLY FUNCTIONAL PROTEIN NANOPARTICLE TARGETING CANCER CELL

机译:高功能蛋白纳米颗粒靶向癌细胞

摘要

To provide a DDS carrier having a cancer cell target ability and a cancer tissue penetrability.SOLUTION: The present invention provides a particle formed by the aggregation of fusion protein containing elastin-like polypeptide, poly acidic amino acid, and iRGD peptide, wherein the fusion protein forms a micelle with the elastin-like polypeptide moiety as a core and the poly acidic amino acid moiety as an outer shell.SELECTED DRAWING: Figure 1
机译:提供具有癌细胞靶向能力和癌细胞组织穿透性的DDS载体。解决方案:本发明提供了由包含弹性蛋白样多肽,聚酸性氨基酸和iRGD肽的融合蛋白聚集形成的颗粒,其中融合蛋白质形成一个以弹性蛋白样多肽部分为核心,多酸性氨基酸部分为外壳的胶束。图1

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