Nanoliposomes for sustained delivery of tacrolimus for treatment of anterior segment disease

摘要

According to the present disclosure, there is provided the use of nanoliposomes in the manufacture of a medicament for the prevention and / or treatment of anterior segment disease. The nanoliposome comprises a plurality of unsaturated lipids and / or saturated lipids forming at least one lipid bilayer encapsulating a hydrophobic drug comprising tacrolimus, wherein the hydrophobic drug and the plurality of unsaturated lipids and / or saturation The lipid has a weight ratio of up to 0.2. The present disclosure also provides such nanoliposomes and methods of preventing and / or treating anterior segment diseases based on the nanoliposomes.