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Non-invasive diagnosis by sequencing 5-hydroxymethylated cell-free DNA
Non-invasive diagnosis by sequencing 5-hydroxymethylated cell-free DNA
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机译:通过对5-羟甲基化无细胞DNA测序进行无创诊断
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摘要
The present application provides a method for sequencing hydroxymethylated cell-free DNA. In certain embodiments, the method adds an affinity tag only to hydroxymethylated DNA molecules in a sample of cfDNA, concentrates the DNA molecules tagged with the affinity tag, and sequences the enriched DNA molecules. Including that.
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