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Automated microscopic blood cell analysis

机译:自动化显微血细胞分析

摘要

The present disclosure describes a single-use test cartridge, blood cell analyzer device, and method for automatically performing microscopic blood cell analysis tasks, such as counting and analyzing blood cells in a biological sample. In one general aspect, a biological sample, such as a measured small amount of whole blood, is placed in a mixing bowl of a disposable test cartridge and then inserted into a hemocytometer. The analyzer also places a known amount of diluent / stain in a mixing bowl and mixes it with blood. The analyzer takes a measured amount of the mixture and dispenses it into the sample cup of the cartridge in fluid communication with the imaging chamber. The geometry of the imaging chamber is chosen so as to maintain the homogeneity of the mixture and prevent blood cells from congesting or clumping as they are transferred into the imaging chamber by the analyzer. Images of all blood cell components in the imaging chamber are counted and analyzed to obtain a complete blood count.
机译:本公开内容描述了一种一次性使用的测试盒,血细胞分析仪装置以及用于自动执行微观血细胞分析任务的方法,例如,对生物样本中的血细胞进行计数和分析。在一个总体方面,将诸如测得的少量全血的生物样品置于一次性测试盒的混合碗中,然后插入血细胞计数器。分析仪还将已知数量的稀释剂/污渍放入混合碗中,并将其与血液混合。分析仪获取一定量的混合物,然后将其分配到与成像室流体连通的盒式样品杯中。选择成像室的几何形状,以保持混合物的均匀性,并防止血细胞在通过分析仪转移到成像室中时发生充血或结块。计数并分析成像室中所有血细胞成分的图像,以获得全血细胞计数。

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