Provided are: an aqueous solution containing ozone nanobubbles that can not only stably sustain the strong bactericidal power or antibacterial power of ozone but also remarkably suppress the invasion thereof into cells in a biological tissue, etc.; a method for producing the same; and utilization of the aqueous solution containing ozone nanobubbles. In the aqueous solution containing ozone nanobubbles according to the present invention, the average particle size and density of the ozone nanobubbles, said average particle size and density being measured by the ice embedding method with the use of a cryo-transmission electron microscope, are respectively 30 nm or less and 1016 nanobubbles/ml or more, preferably 1-10 nm and 1017 nanobubbles/ml or more. The aqueous solution containing ozone nanobubbles according to the present invention contains ozone nanobubbles which are generated by jetting an aqueous solution containing dissolved ozone from the outside of a tube, said tube being provided with 2 or more small through holes formed in the circumferential direction, through the small through holes under atmospheric pressure or higher and thus bringing the jetted solution into collision in such a manner that water hammer is concentrated at the center of the tube on the same plane parallel to a cross-section in a radial direction of the tube.
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