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EXTRACORPOREAL ARTIFICIAL LIVER AND INSTRUMENT FOR EXTRACORPOREAL ARTIFICIAL LIVER OR LIVER CELL CULTIVATION

机译:体外人工肝及体外人工肝或肝细胞培养仪器

摘要

PROBLEM TO BE SOLVED: To provide an artificial liver using high function liver cells.SOLUTION: [1] There is provided an extracorporeal artificial liver provided with at least one module including the following: a plasma component inlet port and a plasma component outlet port; a plasma component circulation chamber provided with the plasma component inlet port and the plasma component outlet port; and a liver cell cultivation chamber disposed adjacent to the plasma component circulation chamber, which is separated from the plasma component circulation chamber by a separation membrane that transmits ammonia, but does not transmit liver cells, where liver cells having ammonia metabolic ability are cultivated. [2] In the artificial liver described in [1], the plasma component circulation chamber is disposed above the liver cell cultivation chamber.SELECTED DRAWING: Figure 1
机译:解决的问题:为了提供一种使用高功能肝细胞的人造肝脏。解决方案:[1]提供了一种体外人造肝脏,其具有至少一个模块,所述至少一个模块包括:血浆成分入口和血浆成分出口;以及血浆成分入口。血浆成分循环室,其具有血浆成分入口和血浆成分出口。肝细胞培养室与血浆成分循环室相邻设置,该肝细胞培养室由透过氨但不透过肝细胞的分离膜与血浆成分循环室隔开,在此培养具有氨代谢能力的肝细胞。 [2]在[1]中描述的人造肝脏中,血浆成分循环室设置在肝细胞培养室的上方。

著录项

  • 公开/公告号JP2018186932A

    专利类型

  • 公开/公告日2018-11-29

    原文格式PDF

  • 申请/专利权人 YONEMITSU YOSHIKAZU;GAIA BIOMEDICINE INC;

    申请/专利号JP20170090335

  • 发明设计人 YONEMITSU YOSHIKAZU;HARADA YUI;

    申请日2017-04-28

  • 分类号A61M1/36;C12M3;C12M1/12;C12N5/0735;C12N15/09;C12Q1/68;

  • 国家 JP

  • 入库时间 2022-08-21 12:21:07

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