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Combination of ribavirin with a direct acting antiviral agent to treat HCV patients

机译:利巴韦林与直接作用抗病毒药联合治疗HCV患者

摘要

The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as no more than 12 weeks. In one aspect, the treatment comprises administering at least two direct acting antiviral agents and ribavirin to a subject with HCV infection, wherein the treatment lasts for 12 weeks and does not include administration of interferon, and said at least two direct acting antiviral agents comprise (a) Compound 1 or a pharmaceutically acceptable salt thereof and (b) Compound 2 or a pharmaceutically acceptable salt thereof.
机译:本发明的特征在于用于治疗HCV的无干扰素疗法。优选地,治疗是在较短的治疗持续时间内,例如不超过12周。一方面,该治疗包括向患有HCV感染的受试者给药至少两种直接作用的抗病毒剂和利巴韦林,其中治疗持续12周且不包括干扰素的给药,并且所述至少两种直接作用的抗病毒剂包括( a)化合物1或其药学上可接受的盐和(b)化合物2或其药学上可接受的盐。

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