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METHOD FOR IDENTIFYING INDIVIDUALS WITH SENSITIVITY OR RESISTANCE TO DEAMIDATED WHEAT PROTEIN ALLERGY

机译:鉴定对脱酰胺化的小麦蛋白过敏具有敏感性或抗性的个体的方法

摘要

To provide useful indicators for determining sensitivity or resistance to deamidated wheat protein.SOLUTION: Disclosed is a detection method of sensitivity or resistance to a deamidated wheat protein comprising detecting HLA-DQ genotype of a nucleic acid sample collected from a subject, the detection of any genotype selected from the group consisting of HLA-DQB1*03:03, HLA-DQB1*03:02, HLA-DQB1*05:01, HLA-DQB1*06:09, and HLA-DQB1*02:01 being an indicator of sensitivity, and the detection of any genotype selected from the group consisting of HLA-DQB1*06:01, HLA-DQB1*03:01, HLA-DQB1*06:02, and HLA-DQB1*04:02 being an indicator of resistance.SELECTED DRAWING: None
机译:为提供用于确定对脱酰胺化的小麦蛋白的敏感性或抗性的有用指标。解决方案:公开了一种对脱酰胺化的小麦蛋白的敏感性或抗性的检测方法,该方法包括检测从受试者收集的核酸样品的HLA-DQ基因型,基因型选自HLA-DQB1 * 03:03,HLA-DQB1 * 03:02,HLA-DQB1 * 05:01,HLA-DQB1 * 06:09和HLA-DQB1 * 02:01灵敏度的检测以及选自HLA-DQB1 * 06:01,HLA-DQB1 * 03:01,HLA-DQB1 * 06:02和HLA-DQB1 * 04:02的任何基因型的检测电阻选择。无

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