首页>
外国专利>
Reprogramming of human endothelium into hematopoietic multilineage progenitor cells with deterministic factors
Reprogramming of human endothelium into hematopoietic multilineage progenitor cells with deterministic factors
展开▼
机译:将人内皮细胞重编程为具有确定性因子的造血多谱系祖细胞
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention is directed to generation of hematopoietic multi-lineage progenitors (HMLPs) from endothelial cells (ECs) by effecting forced expression of certain transcription factors in the ECs and culturing the ECs in serum free media in the presence of endothelial feeder cells. The HMLPs generated in accordance with this invention can produce erythroid, lymphoid, myeloid, and megakaryocyte cells. These generated HMLPs can be used in therapeutic treatment of disorders including hematopoietic conditions.
展开▼