An object of the present invention is to perform blood flow dynamics analysis with high accuracy by applying a blood flow change model of a tissue even if an actually captured image is a small image such as a three-phase image. A region of interest is set to the position of a blood vessel and an organ in a flow path of a contrasted blood flow derived from clinical prior knowledge of contrasted hemodynamics based on medical images of a plurality of patients, and pixel values of the region of interest are set. A database 41 measured and stored, which stores at least three phases of a reference normalized signal intensity curve of a predetermined blood vessel, and a parameter related to the relationship between the reference normalized signal intensity curve and the predetermined blood vessel The blood vessel signal value measurement unit 21 that measures the pixel value of the region of interest based on the medical image of the target patient, the reference normalized signal intensity curve, the parameters regarding the relationship between the reference normalized signal intensity curve and the blood vessel, and the blood vessel A temporal contrast intensity curve estimation unit 22 for calculating an indicator of a distance traveled by a contrast agent of a predetermined blood vessel and an indicator of a circulation speed from the signal value and estimating a temporal contrast intensity curve of the predetermined blood vessel[Selected figure] Figure 2
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