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Polymeric biomaterials derived from phenolic monomers and their medical applications

机译:酚类单体衍生的高分子生物材料及其医学应用

摘要

The present invention provides new classes of phenol compounds, including those derived from tyrosol and analogues, useful as monomers for preparation of biocompatible polymers, and biocompatible polymers prepared from these monomelic phenol compounds, including novel biodegradable and/or bioresorbable polymers. These biocompatible polymers or polymer compositions with enhanced bioresorbabilty and processibility are useful in a variety of medical applications, such as in medical devices and conirolied-release therapeutic formulations. The invention also provides methods for preparing these monomeric phenol compounds and biocompatible polymers.
机译:本发明提供了新型的酚​​化合物,包括衍生自酪醇和类似物的那些,其用作制备生物相容性聚合物的单体,以及由这些单体酚化合物制备的生物相容性聚合物,包括新型的可生物降解和/或可生物吸收的聚合物。这些生物相容性聚合物或具有增强的生物再吸收性和可加工性的聚合物组合物可用于多种医疗应用,例如医疗器械和连续释放的治疗制剂。本发明还提供了制备这些单体酚化合物和生物相容性聚合物的方法。

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