Immunoassay method using anti-human BNP fragment (4-32) antibody

摘要

The present invention aims to provide information useful for the diagnosis and prediction of heart disease simply by detecting a specific human BNP fragment and measuring the human BNP fragment ratio only by immunoassay. It is an object of the present invention to provide a method capable of measuring an untreated human BNP fragment (4-32) with a specific antibody. A method for immunoassay of a human BNP fragment (4-32) in a sample, which reacts with a human BNP fragment (4-32), and human full-length BNP (1-32), human BNP fragment (3-32) And an immunoassay method using an antibody that does not react with the human BNP fragment (5-32). Further, the present invention provides a measurement method in which the antibody is an antibody that reacts with a site containing the N-terminus of human BNP fragment (4-32), or an antibody that reacts with human BNP fragment (4-10).