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A new fusion body and its detection method

机译:一种新型融合体及其检测方法

摘要

Based on the findings, a polynucleotide, a novel causal gene for cancer, is analyzed based on this polynucleotide or method for detecting the polypeptide thereof, the kit and primer set for the detection, screening method for the inhibitor of the polypeptide, and sequence To provide a cancer treatment pharmaceutical composition containing the inhibitor.In the detection method of the present invention, a fusion gene encoding a RET fusion protein or fusion protein, or a fusion gene encoding the ncoa4 or rufi1 fusion protein or the fusion protein in the digestive derived samples obtained from the subject, is detected.
机译:基于该发现,基于该多核苷酸或检测其多肽的方法,用于检测的试剂盒和引物组,用于该多肽的抑制剂的筛选方法以及序列T 1来分析多核苷酸,一种新型的癌症致病基因。提供包含抑制剂的癌症治疗药物组合物。在本发明的检测方法中,在从受试者获得的消化衍生样品中检测到编码RET融合蛋白或融合蛋白的融合基因,或编码ncoa4或rufi1融合蛋白或融合蛋白的融合基因。

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