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Multifunctional degradable nanoparticles with control over size and functionalities

机译:可控制尺寸和功能的多功能可降解纳米粒子

摘要

In one aspect, the invention relates to polymers, crosslinked polymers, functionalized polymers, nanoparticles, and functionalized nanoparticles and methods of making and using same. In one aspect, the invention relates to degradable polymers and degradable nanoparticles. In one aspect, the invention relates to methods of preparing degradable nanoparticles and, more specifically, methods of controlling particle size during the preparation of degradable nanoparticles. In one aspect, the degradable nanoparticles are useful for complexing, delivering, and releasing payloads, including pharmaceutically active payloads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
机译:一方面,本发明涉及聚合物,交联聚合物,官能化聚合物,纳米颗粒和官能化纳米颗粒及其制造和使用方法。一方面,本发明涉及可降解的聚合物和可降解的纳米颗粒。一方面,本发明涉及制备可降解纳米颗粒的方法,更具体地,涉及在制备可降解纳米颗粒期间控制粒径的方法。一方面,可降解的纳米颗粒可用于络合,递送和释放有效载荷,包括药物活性有效载荷。该摘要旨在用作特定领域中进行搜索的扫描工具,而并非旨在限制本发明。

著录项

  • 公开/公告号US10442890B2

    专利类型

  • 公开/公告日2019-10-15

    原文格式PDF

  • 申请/专利权人 VANDERBILT UNIVERSITY;

    申请/专利号US201715682278

  • 申请日2017-08-21

  • 分类号A61K9;C08G63/91;C08G63/08;C08G63/78;A61K9/51;A61K49;A61K47/58;A61K47/59;

  • 国家 US

  • 入库时间 2022-08-21 12:16:53

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