首页> 外国专利> Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof

Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof

机译:羧酰胺卤化卟啉的低分子量衍生物,即二氢卟酚和细菌绿素,及其应用

摘要

The present invention relates to carboxamide halogenated porphyrin derivatives, in particular bacteriochlorin or chlorin, of formula (I) use of the same or a pharmaceutically acceptable salt thereof in photodynamic therapy, where the derivatives are able to detect and exhibit the presence of hyperproliferative disorders and, in the presence of an adequate lighting, to treat the same. The present invention also describes a pharmaceutical composition having the carboxamide halogenated porphyrin derivatives, in particular bacteria-chlorin or chlorin, of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of cancer and/or microbial and/or viral infections, in humans or animals.
机译:本发明涉及式(I)的羧酰胺卤代卟啉衍生物,特别是细菌二氢卟酚或二氢卟酚,其盐或其药学上可接受的盐在光动力疗法中的用途,其中所述衍生物能够检测并显示过度增殖性疾病和,在有足够照明的情况下进行处理。本发明还描述了用于治疗癌症和/或微生物和/或病毒感染的药物组合物,所述药物组合物具有式(I)的羧酰胺卤化的卟啉衍生物,特别是细菌-二氢卟酚或二氢卟酚,或其药学上可接受的盐,在人类或动物中。

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