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Azabenzimidazole derivatives as agonists of the AMP-activated protein kinase

机译:氮杂苯并咪唑衍生物作为AMP活化蛋白激酶的激动剂

摘要

The present invention relates to compounds of general formula I, wherein the group R1, X and Y are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the AMP-activated protein kinase (AMPK) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.; embedded image
机译:本发明涉及通式I的化合物,其中基团R 1 ,X和Y如权利要求 1 所定义,其具有有价值的药理学性质,特别是结合AMP激活的蛋白激酶(AMPK)并调节其活性。该化合物适合于治疗和预防可能受该受体影响的疾病,例如代谢疾病,特别是2型糖尿病。 “嵌入式图像”

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