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Acetate salt of buprenorphine and methods for preparing buprenorphine
Acetate salt of buprenorphine and methods for preparing buprenorphine
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机译:丁丙诺啡的醋酸盐及丁丙诺啡的制备方法
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摘要
The present disclosure provides acetate salts of buprenorphine, and its anhydrates, solvates, hydrates, and crystalline forms thereof, where the acetate salts of buprenorphine are essentially free of impurities. The disclosure further provides method of preparing the acetate salts, buprenorphine free base prepared from the acetate salts, other salts prepared from the free base, and pharmaceutical compositions thereof essentially free of impurities.
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