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Polyporus squamosus-derived recombinant lectin specific for sialic acid linkage

机译：猪来源的重组唾液酸连接重组凝集素

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摘要

The present invention relates to a method for producing a Polyporus squamosus-derived PSL1b recombinant lectin, which binds specifically to sialic acid containing glycoconjugates, from an Escherichia coli PSL1b strain (deposit number: KCTC12507BP) or a Pichia pastoris PSL1b strain (deposit number: KCTC12500BP) and a lectin produced thereby. The recombinant lectin of the present invention can be useful as an active ingredient of a composition or a kit for measuring or detecting glycoproteins, glycopeptides, glycolipids, sugar precursors, or oligosaccharides having sialic acid moieties.

机译：本发明涉及一种从大肠杆菌 PSL1b菌株（保藏号）产生源自 Polyporus squamosus 的PSL1b重组凝集素的方法，该凝集素与含唾液酸的糖缀合物特异性结合。：KCTC12507BP）或巴斯德毕赤酵母 PSL1b菌株（保藏号：KCTC12500BP）和由此产生的凝集素。本发明的重组凝集素可用作用于测量或检测具有唾液酸部分的糖蛋白，糖肽，糖脂，糖前体或寡糖的组合物或试剂盒的活性成分。 展开▼

著录项

公开/公告号US10281460B2

专利类型

公开/公告日2019-05-07

原文格式PDF

申请/专利权人 KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;
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申请/专利号US201415037637

发明设计人 SEONGHUN KIM;
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申请日2014-11-14

分类号C07K14/375;G01N33/53;G01N33/569;

国家 US

入库时间 2022-08-21 12:12:03

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机译： POLYPORUS SQUAMOSUS衍生的重组蛋白，用于唾液酸连接

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机译： POLYPORUS SQUAMOSUS衍生的重组蛋白，用于唾液酸连接

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