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Method for screening new drug candidate inhibiting target protein-protein interaction for development of first-in-class drug
Method for screening new drug candidate inhibiting target protein-protein interaction for development of first-in-class drug
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机译:筛选抑制靶蛋白相互作用的新药候选药物开发方法
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摘要
The present invention relates to a method for screening a substance inhibiting protein-protein interactions, and more particularly to a method for screening a substance inhibiting protein-protein interactions, the method comprising using a protein chip having immobilized thereon spots comprising a mixture of a sol-gel material and a protein. According to the invention, a protein chip can be easily manufactured in a 96-well plate using a sol-gel material, whereby an inhibitor that inhibits protein-protein interactions can be easily screened from a library of natural substances.
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