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COMBINATION OF A CARDIAC STEROID AND AN AKT INHIBITOR FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND DISORDERS
COMBINATION OF A CARDIAC STEROID AND AN AKT INHIBITOR FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND DISORDERS
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机译:心脏甾体和AKT抑制剂的组合用于治疗心血管疾病和疾病
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摘要
The present invention relates to pharmaceutical combinations for the treatment of cardiovascular diseases and disorders. More particularly, the invention relates to pharmaceutical combinations comprising a cardiac steroids CS and at least one PI3K/Akt/m TOR inhibitor. The compositions of the invention may particularly be used for reducing the CS dose administered to a subject suffering from a cardiovascular disease or disorders, thereby reducing the side effects associated with CS therapy. The invention further provides methods of treatment of such diseases and disorders using the pharmaceutical combinations.
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机译:本发明涉及用于治疗心血管疾病和病症的药物组合。更具体地,本发明涉及包含心脏类固醇CS和至少一种PI3K / Akt / m TOR抑制剂的药物组合。本发明的组合物可以特别地用于减少给予患有心血管疾病或病症的受试者的CS剂量,从而减少与CS疗法有关的副作用。本发明进一步提供了使用药物组合治疗此类疾病和病症的方法。
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