首页> 外国专利> METHOD FOR ANALYZING CELL, CHIP FOR CELL ANALYSIS, REAGENT FOR CELL ANALYSIS, KIT FOR CELL ANALYSIS, AND APPARATUS FOR CELL ANALYSIS

METHOD FOR ANALYZING CELL, CHIP FOR CELL ANALYSIS, REAGENT FOR CELL ANALYSIS, KIT FOR CELL ANALYSIS, AND APPARATUS FOR CELL ANALYSIS

机译:细胞分析的方法,用于细胞分析的芯片,用于细胞分析的试剂,用于细胞分析的工具包以及用于细胞分析的装置

摘要

According to some aspects, a method for analyzing a cell is provided. The method includes trapping the cell by binding a first molecule to the cell. The method further includes binding a second molecule to the cell. The second molecule includes a binding portion capable of specific binding to a cell-surface molecule of the cell. The second molecule further includes an identifying portion, a labeling portion coupled to the identifying portion, and a stimulus-degradable linker between the binding portion and the identification portion. The method further includes detaching the identifying portion from the binding portion by stimulating the stimulus-degradable linker where the detached identifying portion is coupled to the labeling portion. The method further includes binding the detached identifying portion through specific binding to an identifying portion recognizing molecule and detecting the labeling portion.
机译:根据一些方面,提供了一种用于分析细胞的方法。该方法包括通过将第一分子结合至细胞来捕获细胞。该方法还包括将第二分子与细胞结合。第二分子包括能够与细胞的细胞表面分子特异性结合的结合部分。第二分子进一步包括识别部分,与识别部分连接的标记部分以及在结合部分和识别部分之间的刺激可降解的接头。该方法还包括通过刺激可刺激的可降解的接头将识别部分与结合部分分离,其中分离的识别部分与标记部分偶联。该方法进一步包括通过特异性结合将分离的识别部分结合至识别分子的识别部分并检测标记部分。

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