首页> 外国专利> ADSORBING MATERIAL FOR MULTIPLE PATHOGENIC FACTORS OF SEPSIS AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF

ADSORBING MATERIAL FOR MULTIPLE PATHOGENIC FACTORS OF SEPSIS AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF

机译:败血病多种致病因素的吸附材料及其制备方法和应用

摘要

An adsorbing material for multiple pathogenic factors of sepsis as well as a preparation method and an application thereof are provided. The adsorbing material is formed by coupling a carrier with good mechanical performance and blood compatibility and a ligand with the capacity to adsorb multiple pathogen-associated molecular patterns, and is capable of effectively adsorbing bacterial endotoxin, bacterial genomic DNA, peptidoglycan, lipoteichoic acid, virus RNA, and zymosan from fluids such as blood and the like, and in particular has application value in blood purification for treatment of sepsis.
机译:提供了一种用于败血症的多种致病因素的吸附材料及其制备方法和应用。吸附材料是通过将具有良好机械性能和血液相容性的载体与具有吸附多种病原体相关分子模式的能力的配体偶联而形成的,并且能够有效吸附细菌内毒素,细菌基因组DNA,肽聚糖,脂蛋白酸,病毒RNA和来自诸如血液等流体的酵母聚糖,尤其在血液纯化中用于败血症的治疗具有应用价值。

著录项

  • 公开/公告号US2019054227A1

    专利类型

  • 公开/公告日2019-02-21

    原文格式PDF

  • 申请/专利权人 CHONGQING ZHENGBO BIOTECHNOLOGY CO. LTD.;

    申请/专利号US201615770629

  • 发明设计人 YUE ZHENG;JUN DENG;QINGGUANG LIU;

    申请日2016-10-27

  • 分类号A61M1/34;B01J20/30;B01J20/26;A61M1/02;A61M1/36;A61M1/38;

  • 国家 US

  • 入库时间 2022-08-21 12:07:16

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