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DISSOCIABLE NANOPARTICLES WITH INTER ALIA TRANSITION-METAL COMPLEX CATALYSTS
DISSOCIABLE NANOPARTICLES WITH INTER ALIA TRANSITION-METAL COMPLEX CATALYSTS
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机译:具有相互间过渡金属复杂催化剂的可分解纳米粒子
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摘要
Nanoparticles for use in assay methods for detecting analytes in samples, which comprise a signal inducing agent, e.g. a transition-metal catalyst or a chemiluminophore, a chemiluminophore precursor, a soluble absorber, or a soluble absorber precursor. After binding to an analyte, the nanoparticle is dissociated by a chemical or physical trigger, e.g. an organic solvent or ultrasound, to release the signal inducing agent, which releases a detectable signal via a physical or chemical reaction. The nanoparticles comprising a chemiluminophore, a chemiluminophore precursor, a soluble absorber, or a soluble absorber precursor can also effect chemical reactions that serve as signal amplifiers.
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