METHODS FOR PRODUCING A HIGH HEPATITIS VIRUS TITLE (HEV) AND FOR DETERMINING A HEV PRESENCE AND / OR A SAMPLE AS WELL AS A HEV TITLE TESTING AND A HIGH TITLE GENERATION TEST HEV

摘要

The use of polybrene as a cell culture medium additive used in methods for the generation of high titer and hepatitis virus stocks and assays for hepatitis e titer are provided herein. In addition, a polybrene-containing cell culture medium for high titer hev generation, a method for determining the presence and / or level of hev in a sample, and a hev titration assay using polybrene are provided.