method for the production of at least one product by microbial fermentation, and for the production of ethanol and 2,3-butanediol by microbial fermentation

摘要

It is a process for producing and controlling pyruvate products during the fermentation of a co-containing substrate by a carboxidotrophic acetogenic microorganism. The process involves increasing the concentration of at least one nutrient selected from the group consisting of vitamin b1, vitamin b5, vitamin b7, and mixtures thereof, above the cellular requirement of the microorganism. when concentration is increased, the production of 2,3-butanediol (2,3-bdo) increases while the production of the other metabolites is virtually unchanged. the effect is reversible so that when concentration is decreased, 2,3-bdo production is also decreased. This allows a person to control the ethanol: 2,3-bdo ratio to a desired value which can range from 4: 1 to 1: 2.