METHODS FOR GENERATING AN ACTIVATED PRODUCT AND TO CONTROL MECHANICAL RESISTANCE OF THE COAGLE ON A PLATTER GEL

摘要

The present disclosure relates to the generation of an activated platelet product wherein one or more of the presence or absence of clots, clot formation time (if present), and / or clot mechanical resistance (if present) is controlled. by the presence or concentration of calcium ions during the activation process. In certain embodiments, the concentration of calcium ions is controlled in the presence of pulsed electric fields or a chemical activator (eg, thrombin) as part of the activation process.